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FODZYME® Help Center logo

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Healthcare Providers

Clinical information, resources, patient indications

What is enzyme activity and how is it measured? What is the relationship between enzyme activity and FODMAP breakdown?

Enzyme activity refers to the rate at which a specific enzyme catalyzes a particular biochemical reaction. Often expressed in "international units" (U), it indicates the amount of enzyme required to convert one micromole of substrate per minute under

What is the difference between FODZYME and prescription pancreatic enzymes, like Creon? Does taking FODZYME with other digestive enzymes influence their efficacy?

Pancreatic Enzyme Replacement Therapy (PERT) is used to correct maldigestion and malabsorption in the presence of pancreatic disease. Overall, PERT therapy is designed to re-establish optimal digestive conditions in the presence of deficient enzyme

How would FODZYME be used if a patient also has small intestinal bacteria overgrowth (SIBO)?

SIBO is a condition where excessive amounts of bacteria are present in the small intestine. Impaired gut motility, commonly present with IBS, increases risk for SIBO and there is a high overlap in the two conditions. Treatment for SIBO is multifacete

How can FODZYME® be used to help patients with IBS and other GI conditions, such as Gastroesophageal reflux disease (GERD), diverticulitis and Inflammatory bowel disease (IBD)?

FODZYME® breaks down the FODMAPs in food; it is not intended to diagnose, treat, cure, or prevent any disease. There is a small body of research to indicate that FODMAPs may contribute to symptoms in those with both IBS and GERD and anywhere from 50%

Can HSA/FSA funds be used towards FODZYME?

Yes! We’ve teamed up with TrueMed to help customers save on their FODZYME orders by using their Health Savings Account (HSA) or Flexible Spending Account (FSA) accounts. The process to get qualified for HSA/FSA reimbursements includes three steps:. A

Do you provide patient handouts and resources?

Yes, we offer various handouts to guide patients on how to get the most out of FODZYME®. Download each here:. Enzymes 101: The Chemistry Behind FODZYME®. Diet & Dosing: Foods to Enjoy with FODZYME®. Dining Out & Label Reading Expert Tips. Traveling w

Do you provide free samples for my clients?

We’re more than happy to send your FODMAP-sensitive patients free samples. Please sign up for our Partner’s Program here to get the process started.

How do I become a FODZYME affiliate or ambassador?

We offer an affiliate program to qualified healthcare providers and content creators. Express your interest and apply here. By joining our affiliate program, you agree to comply with affiliate promotion guidelines for dietary supplements as outlined

I’m a healthcare provider. How can I work with FODZYME?

The FODZYME Partner’s Program is designed to help healthcare providers feel confident identifying good candidates for FODZYME and to make sure their patients get the most benefits it provides. Clinicians who are part of the Partners Program gain excl

Are there any contraindications or side effects?

The enzymes used in FODZYME’s formulation have a long history of safety. For instance, the fructan hydrolase is from an Aspergillus species source and is generally recognized as safe (GRAS) in FDA opinion letters by the FDA (see table below). Note th

How does FODZYME affect dietary fiber fermentation and the microbiome?

In a simulated colon [1], we found that short-chain fatty acid (SCFA) production was reduced but not depleted when using FODZYME. This means that FODZYME’s enzymatic approach may be more favorable to overall colonic health than avoiding FODMAPs altog

Which patients are the best candidates for FODZYME?

FODZYME is best for patients with known sensitivities to fructan, lactose, and GOS/galactans. Those with other co-existing conditions or food intolerances may continue to experience symptoms, even when using FODZYME. FODZYME can be particularly helpf

What research is there to support FODZYME’s efficacy?

To date, we’ve conducted in-house trials where we fed 30-40g of fructan to ourselves and brave friends and family members. We conducted these experiments in the most statistically rigorous way and obtained convincing data on the efficacy of FODZYME w

Why do Registered Dietitians (RDs) recommend using FODZYME?

Many Registered Dietitians and nutritionists recommend FODZYME® to their patients. They recognize FODZYME's efficacy and how it enables patients to enjoy home-cooked family meals, when eating out and when traveling.

CEU Webinars for Clinicians

Learn from expert Registered Dietitians about how to provide the best care for patients with gastrointestinal conditions — and earn free CEUs. Culturally-Informed Applications of the Low FODMAP Diet. with speaker Yi Min Teo, MS, RD, CNSC. DOWNLOAD CE